Antibiotics Can Trigger Asthma Cases

The use of antibiotics is not fair was not only trigger the bacteria resistance to antibiotics, but also potentially increase the severity of cases of asthma and allergy at an early age. Thus the results of research conducted by experts from the University of British Columbia.
This finding was due to be published today in the journal EMBO reports. In his study, researchers found that certain antibiotics can destroy the bacteria in the gut that can trigger the development of asthma.
"It has long been known that many children are often exposed to antibiotics - as happened in some developed countries - so they are more susceptible to asthma," says researcher Brett Finlay, a microbiologist from the University of British Columbia.
"Our study is the first experimental evidence that shows how exposure to antibiotics can trigger the development of asthma," he added.
In his research, Finlay and his team examined how the effects of the use of two types of widely used antibiotics such as streptomycin and vancomycin, may affect the ecosystem of bacteria in the gut. Finlay found that vancomycin can change the bacterial community in the gut and increase the severity of asthma (results of tests on mice).
While the use of the same antibiotic in adult mice does not affect mouse susceptibility to asthma. This suggests that the early life of a critical period in building a healthy immune system.
Researchers noted that asthma has affected more than 100 million people worldwide and its prevalence continues to increase on average by 50 percent every decade, particularly among children living in industrialized countries.
Finlay said, in the human intestine, there are around 100 trillion bacteria, and contains more than 1,000 species of bacteria. "Although not completely understood, but micro-organisms, known as" gut flora "actually made some very useful functions for humans," said Finlay.
"Modern social practices, such as improved methods of sanitation and widespread use of antibiotics, presumably as a cause of loss of species of good bacteria in our gut that may play an important role for healthy immune system," said Finlay.
Finlay reiterated, giving antibiotics to children may be able to disrupt the normal life of the bacteria, so it should not be underestimated.
The study was funded by the Canadian Institutes of Health Research (CIHR). Marc Ouellette, Scientific Director of CIHR said, "has been recognized that microbes play an important role in human health - and we found that disruption of the bacteria has been associated with several chronic health conditions.
An important result of the team of Prof. Finlay confirmed that "the administration of antibiotics to young children, which disrupt the normal bacterial flora, should not be taken lightly."http://health.kompas.com/read/2012/03/17/11571864/Antibiotik.Bisa.Memicu.Kasus.Asma