Initial research conducted by experts showed the potential and benefits of the use of diabetes drug that has been widely known that metformin on cardiovascular health. Animal studies conducted by scientists from the Sahlgrenska Academy University of Gothenburg, Sweden indicate that metformin may provide protective effects on the heart.
In the study, researchers conducted experiments to mice to see the effects of metformin. This study is the result of cooperation with scientists from Naples and has been published in the journal Diabetes on February 22, 2012.
The results revealed that the use of metformin may help improve cardiac pumping capacity, improves the energy balance, reducing the accumulation of fat, and limit the loss of the number of heart cells die.
Long-term effects
In his study, researchers also conducted experiments using other types of diabetes medications (except metformin) to determine the extent to which a protective effect on the heart. Results showed that animals treated with other types of diabetes medications, do not get a positive benefit on the heart.
"The animals used in this study were given metformin for a year, so its effects last a long time," said Jorgen Isgaard, as the leader of the study.
Recent studies in patients
Use of diabetes drugs has been shown to cause some serious side effects in patients with heart disease. Rosiglitazone for example, recently withdrawn because of side effects on the heart. Meanwhile, metformin also sometimes have side effects, especially in patients with renal failure.
"Our results continue to strengthen the indication for use of metformin for diabetes drug, and we hope the future will do a study of actual patients," said Isgaard.http://health.kompas.com/read/2012/03/28/17435680/Obat.Diabetes.Bantu.Cegah.Sakit.Jantung
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